Pittsburgh Pirates at New York Yankees 9/21/22 - MLB Picks & Predictions

Last Updated: 09/20/2022 at 10:57 PM ET

Pittsburgh Pirates at New York Yankees  9/21/22 - MLB Picks & Predictions

The Pittsburgh Pirates play the second and final game of a two-game interleague series on the road Wednesday against the New York Yankees. Pittsburgh dropped to 55-92 following its 7-3 loss to the New York Mets on Sunday. Pittsburgh was swept in its four-game series by New York and the Pirates are last in the National League Central, out of postseason contention. Catch up on the latest in the baseball trends and betting odds with our free MLB previews.

Center fielder Bryan Reynolds is batting .256 to lead Pittsburgh and has team highs in home runs with 23, RBIs with 54, hits with 125 and an on-base percentage of .335. Oneil Cruz is second in both home runs with 17 and RBIs with 51. On Wednesday, the Pittsburgh Pirates will send Roansy Contreras to the mound. The right-hander is 5-4 with a 3.24 ERA, 74 Ks and 35 BBs.

New York improved to 88-58 following its 12-8 victory over the Milwaukee Brewers on Sunday. New York snapped a two-game losing streak with its victory on Sunday. New York has won five of the last seven and the Yankees have a 5 ½-game lead at the top of the American League East with only 16 games remaining on the regular season schedule.

Center fielder Aaron Judge is batting .316 with 59 home runs, 127 RBIs, 166 hits and an on-base percentage of .419 to lead New York in each category. First baseman Anthony Rizzo is second in both home runs with 31 and RBIs with 72. On Wednesday, the New York Yankees will send Luis Severino to the mound. The right-hander is 5-3 with a 3.45 ERA, 95 Ks and 25 BBs.

Pittsburgh has had a very disappointing season, but one bright spot is that the Pirates have won four of the last six when playing head-to-head against the New York Yankees. Pittsburgh's Roansy Contreras has had five consecutive strong starts allowing five earned runs on 18 hits across 27 ⅓ innings. Pittsburgh has won three of the five. New York starting pitcher Luis Severino is coming off the 60-day injury list. Final Score Prediction, Pittsburgh Pirates win 6-5.

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