Pirates vs Twins Picks and Prediction – 7/12/2025

Target Field will play host to a Saturday afternoon MLB interleague clash between the Pittsburgh Pirates and the Minnesota Twins. Be ready for the baseball season with all of our MLB predictions. The Pirates (38-57) have dropped 36 of their first 48 road games and are trapped in the NL Central Division basement. Last night Pittsburgh batters went 1-for-8 with runners in scoring position and left eight men on base during a 2-1 road loss against Minnesota. 

Rookie right-hander Mike Burrows (1-2 3.63 ERA) will make his ninth career major league start for the Pirates. Through 39 plus innings, Burrows has retired 41 batters by strikes and owns a respectable 1.31 WHIP.

The Minnesota Twins are eight games above .500 at home and are trying to stay in contention in the AL Wild Card race. During Friday’s home victory, Minnesota closer Jhoan Duran struck out consecutive batters with the tying run on second base to nail down his 15th save. DH Trevor Larnach’s two-run blast in the fourth inning was all the offense the Twins (46-48) would need on the evening. 

Minnesota manager Rocco Baldelli has yet to name a starting pitcher for this contest. The Twins currently rank 21st in the majors with a 4.14 ERA and have logged just 25 quality starts.

Minnesota SP Pablo Lopez (shoulder) will resume throwing and is eligible to return from the 60-day injured list next month. Through 95 games, Pittsburgh ranks 29th in OPS and 29th in runs scored. For the season, Minnesota ranks 18th in OPS and 21st in runs scored. Take the over. Final Score Prediction, Minnesota Twins win 6-5.