Pirates vs Tigers Picks and Prediction – 6/18/2025

In Wednesday night MLB interleague action, the Pittsburgh Pirates will take on the Detroit Tigers from Comerica Park. Be ready for the baseball season with all of our MLB predictions. The Pirates (29-45) have dropped 26 of their first 36 road games and are stuck in the NL Central Division basement. Last night, veteran Pittsburgh DH Andrew McCutchen doubled and scored a run during a 7-3 road loss against Detroit. 

Thirty-four year old left-hander Andrew Heaney (3-5 3.33 ERA) is quietly pitching well for the Pirates. In his last start, Heaney (6 IP) gave up three runs and fanned seven batters during a 3-2 road loss against Chicago.

The Detroit Tigers have won 25 of their first 36 home games and own the best overall record in the majors. During Tuesday’s home victory, SS Javier Baez went 3-for-4 and crushed two of Detroit’s four home runs. SP Casey Mize (7-2) allowed three runs (2 ER) across six solid frames to earn the win for the Tigers, who improved to 47-27 on the year. 

Detroit manager A.J. Hinch will turn to AL Cy Young Award winner Tarik Skubal (7-2 1.99 ERA) on Wednesday. Through 90 plus innings, Skubal has retired 111 batters by strikes and leads the majors with a ridiculous 0.81 WHIP.

Detroit SP Reese Olson (finger) is on a rehab assignment with Triple-A Toledo and is expected to return later this month. Through 74 games, Pittsburgh ranks 29th in OPS and 30th in runs scored. For the season, Detroit ranks 9th in OPS and 6th in runs scored. Take the under. Final Score Prediction, Detroit Tigers win 4-1.