Pirates vs Diamondbacks Picks and Prediction – 5/27/2025

By: Cameron Ross |

Last Updated: 05/25/2025 at 10:26 PM ET

Pittsburgh Pirates at Arizona Diamondbacks 05/26/25 - MLB Picks & Predictions
Game Start: 5/27/2025, 12:10 AM UTC
Latest Odds: ARI -185 ; O/U 9

Pirates vs Diamondbacks Prediction

The Pittsburgh Pirates will be on the road Monday night with game one of three in Arizona against the Diamondbacks. Pittsburgh has been terrible this season with just 19 wins through 53 games played but have lost just two of the last six overall coming into Monday. Offensively Pittsburgh is terrible with a .222 team batting average the Pirates scored 159 runs on 387 hits. The Pittsburgh pitching has been solid enough however with the 3.99 team ERA this season. Stay in the loop with our MLB Picks.

Andrew McCutchen leads Pittsburgh offense this season with a .255 batting average. Ke’Bryan Hayes is a .234 batting average to go along with the team leading 44 hits. O'Neill Cruz supplies the power for Pittsburgh leading the team with 10 home runs. Bryan Reynolds has a .212 batting average but leads Pittsburgh with 27 RBI's this year.

The Arizona Diamondbacks will be back on their home field Monday with 26 wins 26 losses on the year riding a 4 game losing streak following one run loss against Saint Louis. Offensively Arizona hits the ball well with a .255 team batting average and have scored 264 runs on 450 hits this season. The Arizona pitching has struggled however with a 4.68 ERA and have allowed 17 total runs over their last four losses.

Geraldo Perdomo leads the Arizona Diamondbacks on offense this season with a .309 batting average and a .404 OBP. Corbin Carroll has supplied the power to the team leading the way with 15 home runs and has posted a team high 58 hits. Eugenio Suarez has a .219 batting average to go along with fourteen home runs and a team high 38 RBI's this season.

Pirates vs Diamondbacks Pick Analysis

The Arizona Diamondbacks are the better team in this matchup and will do the job on Monday. Look for Arizona to control this game from the opening pitch as they overwhelm a lackluster Pittsburgh team. Take it out of back Monday to kick off the new week with a win at home against Pittsburgh. Final Score Prediction, Arizona Diamondbacks win 7-3.

Our Free MLB Pick for Arizona Diamondbacks vs Pittsburgh Pirates

Arizona Diamondbacks -185