Phillies vs Nationals Picks and Prediction – 3/29/2025

By: Thomas Pemberton |

Last Updated: 03/28/2025 at 8:38 PM ET

Philadelphia Phillies at Washington Nationals 03/29/25 - MLB Picks & Predictions
Game Start: 3/29/2025, 8:05 PM UTC
Latest Odds: PHI -155 ; O/U 8.5

Phillies vs Nationals Prediction

The Philadelphia Phillies resume their series in Washington on Saturday against the Nationals. The Phillies are 1-0 to start the season. Philadelphia beat Washington 7-3 in their season opener. The Phillies had eight hits in the win and allowed just five hits. Stay up to date with our expert's MLB Picks. 

Jesus Luzardo will make the start on the mound for the Philadelphia Phillies. Luzardo pitched for the Miami Marlins for the last four seasons. Luzardo has not produced a winning record over his last four seasons. Luzardo started 12 games a season ago and posted a 5.00 ERA. 

The Washington Nationals were leading the Phillies 1-0 through five innings yesterday. The Nationals were led by pitcher MacKenzie Gore. Gore pitched 6 innings allowing just one hit and had 13 strikeouts. Luis Garcia and Keibert Ruiz each had two hits and an RBI in the loss. 

Jake Irvin will make the start on the mound for the Washington Nationals. Irvin will pitch his third season for the Nationals. Irvin started 33 games last season and went 10-14 with a 4.41 ERA. Irvin is hoping to produce his first winning season in the MLB. 

Phillies vs Nationals Pick Analysis

The Philadelphia Phillies are road favorites in Washington on Saturday. The Phillies are the better team in this matchup but the value is in the total. The ball should be flying with beautiful weather expected on the east coast. Both starting pitching are hoping to find a win to start the season as they have had their struggles in previous seasons. Final Score Prediction, Philadelphia Phillies win but the play is on the over 6-4. but the play is on the OVER. 

Our Free MLB Pick for Washington Nationals vs Philadelphia Phillies

OVER 8.5