Phillies vs Blue Jays Picks and Prediction – 6/5/2025

In Thursday afternoon MLB interleague action, the Philadelphia Phillies will battle the Toronto Blue Jays from the Rogers Centre. Be ready for the baseball season with all of our MLB predictions. The Phillies (37-24) have won 18 of their first 30 road games and trail NL East Division leading New York by one game. Last night, OF Nick Castellanos’ solo shot was all the offense Philadelphia could generate during a 2-1 road loss against Toronto. 

Twenty-seven year old southpaw Jesus Luzardo (5-1 3.58 ERA) will head to the hill for the Phillies in this contest. Last time out, Luzardo was roughed up for 12 runs and recorded just ten outs during an ugly 17-7 home loss versus Milwaukee. 

The Toronto Blue Jays have won seven of their previous ten games and are 5.5 games behind New York for the top spot in the AL East Division. On Wednesday, Toronto walked it off in the ninth inning on a Alejandro Kirk single that scored Vladimir Guerrero Jr. with the winning run. Bo Bichette added an RBI triple for the Blue Jays (32-29), who improved to 21-13 at home. 

Toronto skipper John Schneider will give the nod to veteran righty Chris Bassitt (5-3 3.80 ERA) on Thursday. In his last start, Bassitt (5 IP) gave up seven hits and five runs during an 11-7 home victory versus the Athletics. 

Toronto OF Anthony Santander received a platelet-rich plasma injection in his injured left shoulder and hopes to return later this month. Through 61 games, Philadelphia ranks 5th in OPS and 7th in runs scored. For the season, Toronto ranks 11th in OPS and 17th in runs scored. Take the Blue Jays to win at home. Final Score Prediction, Toronto Blue Jays win 6-2.