Phillies vs Rays Picks and Prediction – 5/6/2025

In Tuesday night MLB interleague action, the Philadelphia Phillies will travel to Steinbrenner Field to take on the Tampa Bay Rays. Be ready for the baseball season with all of our MLB predictions. The Phillies (19-15) have dropped nine of their first 15 road games and are 2.5 games behind NL East Division leading New York. On Sunday, Bryce Harper and Kyle Schwarber each homered during an 11-9 home loss versus Arizona in ten innings. 

Thirty-four year old righty Zack Wheeler (2-1 3.48 ERA) remains one of the most dominant pitchers in baseball. In his last start, Wheeler (6.2 IP) allowed two runs and struck out seven batters during a 7-6 home victory versus Washington. 

The Tampa Bay Rays are four games below .500 at home and are three games off the pace in the AL East Division race. On Sunday, 1B Jonathan Arranda went 3-for-4 with a home run and three RBIs to lead Tampa Bay to a 7-5 road victory against New York. SP Taj Bradley (3-2) allowed two runs in five plus innings to earn the win for the Rays, who improved 16-18 overall.

Tampa Bay manager Kevin Cash will give the nod to right-hander Drew Rasmussen (1-2 2.64 ERA) on Tuesday. Last time out, Rasmussen (5 IP) gave up six hits and three runs during a 3-0 home loss versus Kansas City.  

Tampa Bay OF Josh Lowe is currently on the 10-day injured list with an oblique injury and hopes to return later this month. Through 34 games, Philadelphia ranks 10th in OPS and 13th in runs scored. For the season, Tampa Bay ranks 21st in OPS and 21st in runs scored. Take the Phillies to win on the road. Final Score Prediction, Philadelphia Phillies win 6-2.