Phillies vs Cardinals Picks and Prediction – 4/13/2025

By: Jeremy O’Quinn |

Last Updated: 04/12/2025 at 10:31 PM ET

Philadelphia Phillies at St. Louis Cardinals 04/13/25 - MLB Picks & Predictions
Game Start: 4/13/2025, 6:15 PM UTC
Latest Odds: PHI -190 ; O/U 8

Phillies vs Cardinals Prediction

The Philadelphia Phillies will be returning to Busch Stadium on Sunday, where they will wrap up their series against the Atlanta Braves. Get the rest of our free MLB picks here! Philadelphia has gone 9-5 thus far which places them second in the NL East. The Phillies have dropped 2 of their last 3 games, however they are coming off a 4-1 victory on Saturday afternoon. Zack Wheeler is expected to be Philadelphia’s starting pitcher on Thursday, he’s posted a 3.44 ERA through 18 innings of play this year. The Phillies are scoring 4.3 runs per game, while giving 3.5 defensively.

The St. Louis Cardinals sit fourth in the NL East, putting together a 6-8 record. St. Louis has dropped 7 of their last 10 games, most recently suffering a 4-1 loss against this Phillies squad on Saturday. Matthew Liberatore will be the Cardinals’ starting pitcher on Monday, he’s posted a 5.84 ERA through 12 innings on the mound this year. St. Louis is averaging 10.2 hits and 5.7 runs per game, while giving up 5.7 runs a game defensively.

Phillies vs Cardinals Pick Analysis

The Phillies hope to build off Saturday’s win, while St. Louis looks to bounce back and close this series out with a win. Expect Wheeler to take care of business on Sunday, leading Philadelphia to cover the -1.5 spread. Final score prediction, Phillies win 6-3.

Our Free MLB Pick for St. Louis Cardinals vs Philadelphia Phillies

Philadelphia Phillies -1.5