Phillies vs Pirates Picks and Prediction – 6/6/2025

Citizens Bank Park will play host to a Friday night MLB clash between the Pittsburgh Pirates and the Philadelphia Phillies. Be ready for the baseball season with all of our MLB predictions. The Pirates have dropped 22 of their first 31 road games and are trapped in the NL Central Division cellar. Pittsburgh’s anemic offense is a big reason for their current standing, but OF Oneil Cruz leads the club with 12 home runs and 22 stolen bases. 

Thirty-two year old righty Joe Ross (2-1 4.34 ERA) will make his first start of the year for the Phillies. Ross has made 21 appearances out of the bullpen for Philadelphia and has fanned 22 batters across 29 frames. 

The Philadelphia Phillies have won 19 of their first 31 home games and trail NL East Division leading New York by 1.5 games. On Thursday, Philadelphia batters managed just five hits during a 9-1 road loss against Toronto. SP Jesus Luzardo (5-2) was tagged for eight runs and recorded just seven outs for the Phillies, who fell to 37-25 overall.

Twenty-eight year old southpaw Bailey Falter (4-3 3.14 ERA) has been quietly pitching well for the Pirates. Last time out, Falter allowed just two hits across six plus scoreless frames during a 5-0 road victory against San Diego. 

Philadelphia SP Aaron Nola (ankle) will be shutdown from throwing due to right side stiffness and his timetable to return is unclear. Through 62 games, Philadelphia ranks 7th in OPS and 7th in runs scored. For the season, Pittsburgh ranks 27th in OPS and 29th in runs scored. Take the Pirates to win at home. Final Score Prediction, Pittsburgh Pirates win 6-2.