Phillies vs Mets Picks and Prediction – 4/23/2025

By: Eddie Kline |

Last Updated: 04/22/2025 at 10:41 PM ET

Philadelphia Phillies at New York Mets 04/23/25 - MLB Picks & Predictions
Game Start: 4/23/2025, 5:10 PM UTC
Latest Odds: PHI -120 ; O/U 7.5

Phillies vs Mets Prediction

NL East Division rivals will collide on Wednesday afternoon, when the Philadelphia Phillies and the New York Mets conclude their series from Citi Field. Be ready for the baseball season with all of our MLB predictions. The Phillies (13-11) have dropped seven of their first 11 road games and trail the Mets by four games for first place. Last night, Philadelphia SP Cristopher Sanchez (2-1) departed after giving up two runs in two innings during a 5-1 road loss.

Thirty-four year old righty Zach Wheeler (2-1 3.73 ERA) is still one of the more dominant starting pitchers in baseball. Last time out, Wheeler (7 IP) allowed two runs and struck out 13 batters during a 7-2 home victory versus Miami. 

The New York Mets are off to a torrid 11-1 start at home and are tied for the best overall record in the majors. During Tuesday’s home victory, leadoff hitter Francisco Lindor sparked the New York offense with three hits and a run scored. SP Griffin Canning (3-1) scattered eight hits and allowed one run in five innings to earn the win for the Mets, who improved to 17-7 overall.  

New York manager Carlos Mendoza will give the ball to talented left-hander David Peterson (1-1 3.27 ERA) on Wednesday. In his last start, Peterson (5.1 IP) gave up three runs and fanned nine batters during a 5-4 home victory versus St. Louis. 

Phillies vs Mets Pick Analysis

New York C Francisco Alvarez (hand) is currently on a rehab assignment and hopes to return later this month. Through 24 games, Philadelphia ranks 6th in OPS and 9th in runs scored. For the regular season, New York ranks 17th in OPS and 16th in runs scored. Take the Mets to win at home. Final Score Prediction, New York Mets win 4-3.

Our Free MLB Pick for New York Mets vs Philadelphia Phillies

New York Mets +100