Phillies vs Rockies Picks and Prediction – 5/22/2025

This Wednesday, Taijuan Walker and the Philadelphia Phillies take on Carson Palmquist and the Colorado Rockies at Coors Field in the third game of their early-week series. Get our free MLB Picks all season long! The Phillies, now 29-18, are coming off a dominant 9-3 win on Monday, showcasing both power at the plate and consistency on the mound.

Walker will make his return to the rotation and aim to build off Philadelphia’s momentum. His ability to keep the ball in the yard will be critical in the hitter-friendly conditions of Denver. The Phillies’ offense continues to click, with production coming from the top and bottom of the order.

The Rockies, now 8-39, are stuck in a historically bad stretch and have dropped seven of their last eight. Palmquist will make his first big league start, and while he brings some promise, facing one of the hottest lineups in the league is a steep challenge for any rookie pitcher.

Colorado must play clean defense and find some early offense to avoid another lopsided defeat. Philadelphia will look to jump on Palmquist early and take advantage of a Rockies bullpen that has been overworked and ineffective through much of the season.

With a hot lineup and the advantage in experience on the mound, Philadelphia should stay in control. Palmquist may show flashes, but the Phillies’ firepower and Walker’s presence should be enough to seal it. Take Walker and the Phillies to dominate this game from start until finish. Final Score Prediction: Phillies win 7-2.