Yankees vs Mariners Picks and Prediction – 5/14/2025

In Wednesday afternoon MLB action, the New York Yankees and the Seattle Mariners will wrap up their series from T-Mobile Park. Be ready for the baseball season with all of our MLB predictions. The Yankees (24-18) are a game above .500 on the road and hold a 2.5 game lead over Boston for the top spot in the AL East Division. Last night, New York batters went 0-for-14 with runners in scoring position and left 11 men on base during a 2-1 road loss in 11 innings. 

Twenty-five year old righty Will Warren (2-2 4.75 ERA) will take the mound for the Yankees in this matchup. In his last start, Warren (7.1 IP) allowed one run and fanned seven batters during a 10-2 road victory against the Athletics. 

The Seattle Mariners have won 13 of their first 23 home games and are sitting atop a tightly contested AL West Division standings. On Tuesday, Seattle walked it off on a J.P. Crawford single that scored Leody Taveras with the winning run, SP Bryan Woo fired six plus shutout frames and did not factor in the decision for the Mariners (23-18), who snapped a four-game losing streak.

The Mariners will counter with thirty-two year old righty Luis Castillo (3-3 3.95 ERA) on Wednesday. Last time out, Castillo (5 IP) was tagged for seven hits and five runs during a 6-3 home loss versus Toronto. 

New York 3B Oswaldo Cabrera suffered a left ankle fracture and his timetable to return is uncertain. Through 42 games, New York ranks 1st in OPS and 1st in runs scored. For the season, Seattle ranks 9th in OPS and 9th in runs scored. Take the over. Final Score Prediction, New York Yankees win 6-4.