Yankees vs Pirates Picks and Prediction – 4/6/2025

By: David Anicetti |

Last Updated: 04/05/2025 at 7:31 PM ET

New York Yankees at Pittsburgh Pirates 04/06/25 - MLB Picks & Predictions
Game Start: 4/6/2025, 5:35 PM UTC
Latest Odds: NYY -150 ; O/U 8.5

Yankees vs Pirates Prediction

The New York Yankees complete a three-game series on the road Sunday versus the Pittsburgh Pirates. New York is 5-2 and leads the American League East by a half-game over Toronto. The Yankees defeated the Pirates 9-4 in the opening game of the series on Friday. Aaron Judge hit his sixth home run of the season in his 1,000th game with the Yankees. Keep up to date with all the MLB action with our expert MLB picks.

Aaron Judge is batting .379 with six home runs, 17 RBI, and 11 hits to lead New York in each of the four categories. Ben Rice is the leader in on-base percentage at .480. New York has a team batting average of .288 and a slugging percentage of .621. On Sunday, New York will send Will Warren to the mound. The right-hander is 0-0 with a 3.60 ERA, 4 Ks, and 4 BBs.

The Pittsburgh Pirates dropped to 2-6 following Friday’s five-run loss to the Yankees. Pittsburgh is 4th in the National League Central, three games behind the first-place Chicago Cubs. In Friday's loss, Pittsburgh starter Mitch Keller gave up seven runs on eight hits across only 3.2 innings. Ke’Bryan Hayes and Bryan Reynolds each hit home runs for the Pirates

Isiah Kiner-Falefa is batting .360 to lead Pittsburgh and has team highs in hits with nine and an on-base percentage at .467. Oneil Cruz is the leader in home runs with two, and Adam Frazier is the leader in RBI with four. Pittsburgh is batting .205 with a .301 slugging percentage. On Sunday, Pittsburgh will send Andrew Heaney to the mound. The left-hander is 0-0 with a 1.80 ERA, 2 Ks, and 1 BBs.

Yankees vs Pirates Pick Analysis

New York will win on Sunday, but the play here is UNDER. The UNDER has cashed in four of Pittsburgh's last five and 11 of the Pirates’ last 16 versus an AL opponent. New York starter Will Warren gave up two runs on one hit across five innings but struggled with control, walking four. Pittsburgh starter Andrew Heaney gave up one run on four hits across five innings versus Miami last Sunday. Final Score Prediction, New York Yankees win but our best play is UNDER 4-2.

Our Free MLB Pick for Pittsburgh Pirates vs New York Yankees

Under 8.5