Yankees vs Angels Picks and Prediction – 5/28/2025

By: Thomas Pemberton |

Last Updated: 05/26/2025 at 11:41 PM ET

New York Yankees at Los Angeles Angels 05/27/25 - MLB Picks & Predictions
Game Start: 5/28/2025, 1:38 AM UTC
Latest Odds: NYY -186 ; O/U 8.5

Yankees vs Angels Prediction

The Los Angeles Angels remain at home on Tuesday with the New York Yankees in town. The Angels are 4th in the AL West.. Los Angeles has won eight of their last ten games. The Angels are averaging 4.3 runs scored per game with 7.5 hits per game. Stay up to date with our expert's MLB Picks. 

Tyler Anderson will make his 11th start on the hill for the LA Angeles. Anderson is 2-1 on the season with 55 innings pitched. Anderson has 43 strikeouts and carries a 3.60 ERA. Anderson carries a losing home field record. The LA Angels carry a 4.99 team ERA. 

The New York Yankees are the leaders of the AL East. The Yankees have won eight of their last ten games and carry a winning home field record. New York entered this series riding a two game win streak on Monday. The Yankees are averaging 5.7 runs scored per game. 

Carlos Rodon will make his 12th start on the hill for the NY Yankees. Rodon is 6-3 on the season with 65.2 innings pitched. Rodon has 80 strikeouts and carries a 2.88 ERA. Rodon pitched 6 innings in his last start allowing 2 hits and no runs.

Yankees vs Angels Pick Analysis

The New York Yankees are road favorites on Tuesday. The Yankees are averaging 8.9 hits per game and win the pitching matchup. New York leads the MLB with 86 team home runs. The value is in the total. Final Score Prediction, New York Yankees win, but the play is on the over 8-4.

Our Free MLB Pick for Los Angeles Angels vs New York Yankees

OVER 8.5