Mets vs Cardinals Picks and Prediction – 5/3/2025

Busch Stadium will be the scene for a Saturday MLB showdown between the New York Mets and the St. Louis Cardinals. Be ready for the baseball season with all of our MLB predictions. The Mets (22-11) are a game above .500 on the road and hold a 3.5 game lead over Philadelphia for first place in the NL East Division. Last night, OF Brandon Mimmo collected three of New York’s 17 hits and scored three times during a 9-3 road triumph against St. Louis. 

Twenty-nine year old righty Tylor Megill (3-2 1.74 ERA) will take the mound for the Mets in this matchup. Through 31 innings of work. Megill has allowed just one home run and struck out 39 batters while posting a solid 1.13 WHIP.

The St. Louis Cardinals have won ten of their first 16 home games and are trying to climb back into the NL Central Division race. During Friday’s series opener, St. Louis SS Masyn Winn went 3-for-4 and scored a run. SP Sonny Gray (3-1) gave up six runs (4 ER) and lasted just four plus innings for the Cardinals, who fell to 14-19 overall.

The Cardinals will counter with thirty-two year old righty Erick Fedde (1-3 4.68 ERA) on Saturday. Last time out, Fedde (5.2 IP) was rocked for ten hits and seven runs during a 7-1 home loss versus Milwaukee. 

New York SP Sean Manaea (oblique) resumed playing catch and hopes to make his season debut sometime next month. Through 33 games, New York ranks 7th in OPS and 10th in runs scored. For the season, St. Louis ranks 10th in OPS and 11th in runs scored. Take the Mets to win on the road. Final Score Prediction, New York Mets win 5-3.