Mets vs Cardinals Picks and Prediction – 5/3/2025

The New York Mets head to St. Louis on Friday to take on the Cardinals for a weekend series. The Mets are 21-11 on the season and lead the NL East. New York has won six of their last ten games. and are riding a two game losing streak. The Mets are 8-8 on the road this season. New York is averaging 4.8 runs scored per game. Stay up to date with our expert's MLB Picks. 

Clay Holmes will make his 7th start on the mound for the NY Mets. Holmes is 3-1 on the season with 30.2 innings pitched. Holmes has 36 strikeouts and carries a 2.64 ERA. Holmes pitched 5 innings in his last start allowing 4 hits and no runs. The New York are 1st in the MLB with an average of 3 runs allowed per game. 

The St. Louis Cardinals are 14-18 on the season and 4th in the NL Central. The Cardinals are 5-5 over their last ten games and they carry a 10-5 home court record. St. Louis is averaging 9 hits per game which is 3rd best in the MLB. The Cardinals lost to the Red on Thursday 9-1. 

Sonny Gray will make his 7th start on the mound for the St. Louis Cardinals. Gray is 3-0 on the season with 35 innings pitched. Gray has 33 strikeouts and carries a 3.60 ERA. Gray pitched 6 innings in two straight starts. The St. Louis Cardinals carry a 4.08 team ERA. 

The New York Mets are road favorites in St. Louis on Friday. The Mets are hoping to snap a two game losing streak. The St. Louis Cardinals play their best baseball on their home field. Watch for a pitching duel in this matchup. The value is in the total. Final Score Prediction, St. Louis Cardinals win, but the play is on the under 3-2.