Mets vs Cardinals Picks and Prediction – 5/4/2025

By: Cameron Ross |

Last Updated: 05/04/2025 at 12:01 AM ET

New York Mets at St. Louis Cardinals Game 2 05/04/25 - MLB Picks & Predictions
Game Start: 5/4/2025, 10:15 PM UTC
Latest Odds: NYM -155 ; O/U 8.5

Mets vs Cardinals Prediction

The New York Mets come into game two of the doubleheader on Sunday with 22 wins on the year currently the top team in the National League East. New York has relied heavily on their power thus far this season as the Mets have hit 38 home runs to go along with a .424 team slugging percentage. New York has thrived this season offensively having scored 159 runs on 277 total hits. Stay in the loop with our MLB Picks.

Clay Holmes got the start and win for New York in Game 1 of this series giving up three runs on eight hits across 6 innings of work. The New York bullpen was lights out in game one giving up just one hit and no runs over the final three innings in game one. Offensively New York rolled scoring nine runs on seventeen hits. Francisco Alvarez led the way for the New York offense with three hits and five at bats to drive in three runs. Pete Alonso also chipped in heavily with two hits and two RBIs in the game.

The Saint Louis Cardinals limp into game two of the doubleheader on Sunday five games below .500 currently in fourth place in the National League Central. The Saint Louis pitching has been below average this season with a 4.31 ERA but the Cardinals have given up nine runs in each of their last two losses. The Saint Louis power has been mediocre as well with only 30 home and a.395 slugging percentage as a team through 33 games played this season.

Sonny Gray took the loss in Game 1 of this series for Saint Louis giving up six runs on nine hits across 4.1 innings of work. The Saint Louis bullpen was roughed up as well giving up three runs on eight hits over the final four point two innings of work. Masyn Winn and William Contreras led the way for the Saint Louis offense combining for five hits in eight at bats to drive in one run apiece.

Mets vs Cardinals Pick Analysis

New York will have the much better arm on the mound in this game and that will be the difference. In game 2 of a double header New York will have a huge edge with the better starter. Look for New York to thrive against a pitcher with an ERA above 4 Sunday night leading to the win in game 2. Final Score Prediction, New York Mets win 7-3.

Our Free MLB Pick for St. Louis Cardinals vs New York Mets

New York Mets -155