Mets vs Yankees Picks and Prediction – 5/17/2025

By: Eddie Kline |

Last Updated: 05/16/2025 at 11:49 PM ET

New York Mets at New York Yankees 05/17/25 - MLB Picks & Predictions
Game Start: 5/17/2025, 5:05 PM UTC
Latest Odds: NYY -135 ; O/U 9.5

Mets vs Yankees Prediction

The Saturday MLB schedule will get underway with a matinee between the New York Mets and the New York Mets from the Bronx. Be ready for the baseball season with all of our MLB predictions. The Mets (28-17) are a game below .500 at home and hold a two-game lead over Philadelphia for first place in the NL East Division standings. Last night, the Mets went 2-for-9 with runners in scoring position and left 11 men on base during a 6-2 road loss against the Yankees. 

Twenty-nine year old righty Griffin Canning (5-1 2.36 ERA) has been a solid free-agent addition. The Mets have won Canning’s previous five starts and he has allowed just four runs over his last 27 innings of work. 

The New York Yankees have won seven of their last ten games and have opened up a five-game cushion for AL East Division supremacy. During Friday’s home victory, OF Cody Bellinger went 3-for-5 with a pair of runs scored to spark the New York offense. AL MVP Aaron Judge added a pair of hits and scored twice for the Yankees (26-18), who improved to 14-8 at home. 

New York manager Aaron Boone will give the nod to right-hander Clarke Schmidt (1-1 4.73 ERA) on Saturday. Last time out, Schmidt (6 IP) gave up three runs and struck out six batters during an 11-5 road triumph against Seattle. 

Mets vs Yankees Pick Analysis

New York OF Jose Siri (leg) has resumed baseball activities and hopes to return to the lineup early next month. Through 45 games, the Mets rank 5th in OPS and 10th in runs scored. For the season, the Yankees rank 1st in OPS and 2nd in runs scored. Take the Mets to win. Final Score Prediction New York Mets win 6-4.

Our Free MLB Pick for New York Yankees vs New York Mets

New York Mets +115