Mets vs Astros Picks and Prediction – 3/29/2025

The New York Mets complete a three-game series on the road Saturday when playing the Houston Astros. New York opened its regular season on Thursday with a 3-1 loss to Houston. Off-season acquisition Juan Soto was struck out in the top of the 9th Inning with two on as the Mets could produce just one run. Mets starting pitcher Clay Holmes gave up two runs across 4.2 innings to suffer the loss. Keep up to date with all the MLB action with our MLB previews.

Pete Alonso is batting .500 to lead New York after one game and has a team-high .750 on-base percentage. New York did not have a home run on opening day, and Francisco Lindor is the RBI leader with one. New York was held to just six hits by Houston pitching. On Saturday, New York will send Griffin Canning to the mound. Last season, the right-hander was 6-13 with a 5.19 ERA, 130 Ks, and 66 BBs for the Los Angeles Angels.

The Houston Astros are 1-0 after their two-run victory over the New York Mets on Thursday. Framber Valdez pitched seven shutout innings for Houston on opening day, and Josh Hader picked up the save after fanning Soto in the ninth. Yainer Diaz had an RBI single for Houston. Jose Altuve started in left field for the first time in his career after 1,759 starts at second base.

After one game of the regular season, Jake Meyers has a .500 batting average to lead Houston. Meyers is the leader in hits with two and tied for the lead in RBI with Yainer Diaz at one apiece. Houston has a team batting average of .241 and a slugging percentage of .241. On Saturday, the Astros will send Spencer Arrighetti to the mound. Last season, the right-hander was 7-13 with a 4.53 ERA, 171 Ks, and 65 BBs.

Houston starting pitcher Spencer Arrighetti had a solid spring training with a 3.71 ERA and 20 strikeouts, but New York's right-hander Griffin Canning was even better during spring training at 2-1 with a 1.88 ERA and 22 Ks. while posting a 1.12 WHIP. The Mets’ hitters will come to life on Saturday against Houston's pitching and produce plenty of runs for Canning. Final Score Prediction, New York Mets win 7-2.