Twins vs Athletics Picks and Prediction – 6/5/2025

By: Ricky MacKenzie |

Last Updated: 06/03/2025 at 11:23 PM ET

Minnesota Twins at Sacramento Athletics 06/04/25 - MLB Picks & Predictions
Game Start: 6/5/2025, 2:05 AM UTC
Latest Odds: MIN -170 ; O/U 8

Twins vs Athletics Prediction

This Wednesday, Zebby Matthews and the Minnesota Twins look to carry momentum into the second game of the series after a commanding 10-4 victory over the Athletics on Monday. Get our free MLB Picks all season long! Matthews and the Twins will rely on his sharp command and Minnesota’s recent offensive surge to shut down an inconsistent A’s lineup.

The Athletics will start Jeffrey Springs, who was hit hard in his last outing. Facing a hot Twins order, Springs must mix pitches effectively and avoid early trouble. Oakland’s pitching staff has struggled to contain opposing bats, and they’ll need to be nearly flawless to keep this game competitive.

Minnesota’s lineup continues to produce top-to-bottom. Strong performances from the middle order helped break Monday’s game open. With Matthews supported by a steady bullpen and airtight defense, the Twins look well-positioned to handle any pushback from the Athletics.

Oakland’s key to staying in this one is jumping on Matthews early and stringing together hits. If they fall behind, their bullpen has shown little promise in stopping high-powered lineups. Offensive production will be critical for the Athletics if they want to flipping the script from Monday’s loss.

Twins vs Athletics Pick Analysis

Minnesota rides the wave of momentum behind Matthews, delivering a consistent performance on both sides of the ball. Expect a strong showing again at home. The Twins will look to run away with this one early, expect Matthews to get a lighter workload than usual. Take the Twins to dominate this game from start until finish. Final Score Prediction, Minnesota Twins win 6-2.

Our Free MLB Pick for Sacramento Athletics vs Minnesota Twins

Minnesota Twins -170