Twins vs Brewers Picks and Prediction – 5/17/2025

Minnesota has been hot, winning 10 in a row, including an 8-6 and 6-3 sweep over Baltimore. Milwaukee just snapped a three-game skid with a 9-5 win over Cleveland. On the mound, Joe Ryan (3-2, 2.74 ERA, 0.83 WHIP) gets the ball for the Twins while Chad Patrick (2-3, 3.19 ERA, 1.25 WHIP) counters for the Brewers in a righty-righty matchup at American Family Field. First pitch is set for 6:10 PM ET. Elevate your MLB game with our top-notch MLB picks.

After back-to-back wins in Baltimore and a sweep of San Francisco, the Twins are gaining momentum. Joe Ryan continues to be a reliable starter, punching out 54 in 46 innings while holding hitters to a .233 average. Byron Buxton leads the offense with 9 homers and 26 RBIs, and even with injuries to Harrison Bader and Ty France, the lineup is producing enough to support the pitching.

Defensively, the Twins are rock solid, boasting a 3.38 team ERA and 1.17 WHIP. They’ve only allowed 107 walks all year, and the bullpen has held up its end. Even without Erasmo Ramirez, Minnesota is deep enough to maintain pressure late in games. Offensively, the .239 average isn’t eye-popping, but 40 homers and a .310 OBP show they’ve been timely with hits. 

Milwaukee enters the matchup after a strong offensive showing in the series finale at Cleveland, tagging them for nine runs. The Brewers’ offense has been inconsistent, scoring just two combined runs in the previous two games. Christian Yelich leads in home runs and RBIs but is hitting only .205. Rhys Hoskins has been more reliable, hitting .292 with a .396 OBP. Chad Patrick has flashed potential but struggles with command, already issuing 14 walks in 42.1 innings.

On the mound, Milwaukee’s 4.15 team ERA and 1.32 WHIP show a vulnerable rotation and bullpen, especially with key arms like Aaron Civale, Jose Quintana, and Brandon Woodruff on the IL. The Brewers have allowed more runs and walks than Minnesota, and defensively, lacked the sharpness needed to close out games. A strong 12-7 home record helps.

Minnesota has the hotter bats, better pitching, and a dominant arm in Joe Ryan, who’s sporting a 0.83 WHIP and 54 strikeouts in 46 innings. Milwaukee’s pitching staff is banged up, and Chad Patrick has a walk problem that could lead to trouble against a lineup that’s heating up. The Twins’ bullpen and defense give them the edge in a tight matchup. Final Score Prediction: Minnesota Twins win 5-3.