Twins vs Astros Picks and Prediction – 6/15/2025

By: David Anicetti |

Last Updated: 06/14/2025 at 8:41 PM ET

Minnesota Twins at Houston Astros 06/15/25 - MLB Picks & Predictions
Game Start: 6/15/2025, 6:10 PM UTC
Latest Odds: HOU -130 ; O/U 8.5

Twins vs Astros Prediction

The Minnesota Twins complete a three-game series on the road Sunday versus the Houston Astros. The Twins are 36-33 following a 10-3 loss to Houston on Friday in the opening game of the series. The Twins have lost two straight, three of the last four, and six of the last eight. Minnesota struggles at the plate as the Twins are just 20th in batting average. The Twins are second in the American League Central, but trail the first-place Detroit Tigers by nine games. Keep up to date with all the MLB action with our expert MLB picks.

Ty France is batting .276 with 68 hits to lead Minnesota in both categories. Byron Buxton leads in home runs with 11 and RBI with 41, while Ryan Jeffers leads in on-base percentage with .341. Minnesota is batting .244 with a .392 slugging percentage. On Sunday, Minnesota will send Simeon Woods Richardson to the mound. The right-hander is 2-3 with a 5.74 ERA, 39 Ks, and 17 BBs.

The Houston Astros improved to 39-30 following Friday’s seven-run victory over Minnesota. Jose Altoona and Jacob Milton each had three RBI on Friday for the Astros. Houston has won three straight and six of the last eight. The Astros lead the American League West by 4 ½ games over the second-place Seattle Mariners and 5 ½ games over the Texas Rangers.

Jeremy Pena is batting .333 with 89 hits and an on-base percentage of .386 to lead Houston in the three categories. Isaac Paredes leads Houston in home runs with 15 and in RBI with 42. Houston is batting .256 with a .396 slugging percentage. On Sunday, Houston will send Brandon Walter to the mound. The left-hander is 0-0 with a 1.64 ERA, 10 Ks, and 1 BBs.

Twins vs Astros Pick Analysis

Houston has won six of its last eight, while in contrast, Minnesota has lost six of its last eight. Minnesota starting pitcher Simeon Woods Richardson has struggled in each of the last two starts, allowing 12 runs on 16 hits across 8.2 innings. Houston starter Brandon Walter has pitched well in each of his two starts this season, allowing two runs on nine hits across 11 innings. Final Score Prediction: Houston Astros win 6-2.

Our Free MLB Pick for Houston Astros vs Minnesota Twins

Houston Astros -130