Twins vs Reds Picks and Prediction – 6/18/2025

The Minnesota Twins play the second game of a three-game series on the road Wednesday versus the Cincinnati Reds. Minnesota is 36-35 following a 2-1 loss to the Houston Astros on Sunday. Minnesota was swept by Houston in a three-game series, and the Twins have lost four straight. Minnesota is second in the American League Central, 9 games behind the first-place Detroit Tigers. Keep up to date with all the MLB action with our MLB predictions.

Byron Buxton is batting .273 with 11 home runs and 41 RBI to lead Minnesota in the three categories. Ty France is the leader in hits with 68, and Ryan Jeffers is the leader in on-base percentage at .342. Minnesota is batting .242 with a .388 slugging percentage. On Wednesday, Minnesota will send Bailey Ober to the mound. The right-hander is 4-3 with a 4.40 ERA, 57 Ks, and 21 BBs.

The Cincinnati Reds are 37-35 following an 8-4 victory over the Detroit Tigers on Sunday. The Reds were off Monday. Elly De La Cruz had a home run and three RBI for Cincinnati. Cincinnati won two out of three over the American League Central-leading Tigers, and Cincinnati has won seven of its last nine. The Reds are seven games behind the first-place Chicago Cubs in the National League Central.

TJ Friedl is batting .290 with 75 hits and an on-base percentage of .384 to lead Cincinnati in the three categories. Elly De La Cruz leads the Reds in home runs with 16 and in RBI with 50. Cincinnati is batting .248 with a .405 slugging percentage. On Wednesday, Cincinnati will send Nick Lodolo to the mound. The left-hander is 4-5 with a 3.76 ERA, 70 Ks, and 16 BBs.

Minnesota wins at home on Wednesday, but the play here is OVER. The OVER has cashed in seven of Minnesota's last 10 and five of Cincinnati's last six. Minnesota starter Bailey Ober has been hit hard in each of the last two outings, allowing 12 runs on 11 hits across 11.2 innings. Cincinnati starter Nick Lodolo has been hit hard in two consecutive outings, allowing nine runs on 10 hits across 9.1 innings. Final Score Prediction: Minnesota Twins win but our best play is OVER 7-5.