Twins vs White Sox Picks and Prediction – 4/2/2025

The Minnesota Twins will complete a three-game series on the road in the Windy City on Wednesday versus the Chicago White Sox. Minnesota is 0-4 and last in the American League Central, two games behind first place. Minnesota lost to Chicago 9-0 on Monday in the opening game of the series. Minnesota has allowed 28 runs for an average of 7 per game in the first four this season. Keep up to date with all the MLB action with our MLB picks. 

Willi Castro is batting .357 with one home run, three RBI, five hits, and an on-base percentage of .400 to lead Minnesota in each of the five categories. As a team, Minnesota is batting .143 with a .230 slugging percentage. On Wednesday, Minnesota will send Pablo Lopez to the mound. The right-hander is 0-1 with a 3.60 ERA, 3 Ks, and 0 BBs.

The Chicago White Sox are in a three-way tie for first place in the American League Central with Cleveland and Kansas City at 2-2. The White Sox snapped a two-game losing skid with Monday’s nine-run victory. Martin Perez threw six shutout innings in his debut with the White Sox on Monday. The White Sox have been receiving excellent performances on the mound with a team ERA of 0.75.

Andrew Benintendi is batting .231 with two home runs, six RBI, and an on-base percentage of .375 to lead Chicago in the four categories. Michael A. Taylor is the leader in hits with three. Chicago is batting .210 with a .411 slugging percentage. On Wednesday, Chicago will send Sean Burke to the mound. The right-hander is 1-0 with a 0.00 ERA, 3 Ks, and 0 BBs. 

 Chicago has a team ERA of just 0.75 and will keep the Minnesota hitters in check on Wednesday. Minnesota starter Pablo Lopez was hit hard last time out on opening day, allowing four runs on eight hits across five innings in a 5-3 loss to St. Louis. Chicago starter Sean Burke gave up no runs on three hits across six innings and an opening day 8-1 victory over the Los Angeles Angels. Final Score Prediction, Chicago White Sox win 7-2.