Twins vs White Sox Picks and Prediction – 3/31/2025

The Minnesota Twins open a three-game series on the road Monday versus the Chicago White Sox. Minnesota is 0-2 following its 5-1 loss to the St. Louis Cardinals on Saturday and will complete a three-game series with the Cardinals on Sunday. Minnesota has been outscored in its first two games of the regular season by a combined 10-4 as the Twins have not performed well at the plate. Keep up to date with all the MLB action with our MLB picks.

Trevor Larnach is batting .500 to lead Minnesota and has team highs in hits with three and an on-base percentage of .571. Harrison Bader has Minnesota's only home run of the season. Willi Castro is the leader in RBI with two. On Monday, the Minnesota Twins will send Chris Paddack to the mound. Last season, the right-hander was 5-3 with a 4.99 ERA and 79 Ks.

The Chicago White Sox are 1-1 following a 1-0 loss to the Los Angeles Angels on Saturday. Chicago opened its regular season with an 8-1 victory over the Angels on Thursday, and both had an off day on Friday. Chicago had just two hits in Saturday's loss. Chicago’s Mike Clevinger pitched one inning, allowing one hit and one run while walking one, to suffer the loss.

Andrew Benintendi is batting .333, with one home run, two hits, three RBIs, and an on-base percentage of .500 to lead Chicago in each of the five categories. Two other players also have one home run for the Chisox. Chicago is batting .183 with a slugging percentage of .357. On Monday, Chicago will send Martin Perez to the mound. Last season, the left-hander was 5-6 with a 4.53 ERA and 107 Ks. 

The Chicago White Sox will win at home on Monday when opening a three-game series versus the Minnesota Twins. Chicago has won six of the last nine overall and seven of the last eight played at home. Chicago starting pitcher Chris Paddack will keep the Minnesota bats quiet for another game. Minnesota is batting just .172 as a team with a .266 slugging percentage. Final Score Prediction, Chicago White Sox win 4-2.