Twins vs Red Sox Picks and Prediction – 5/4/2025

By: Eddie Kline |

Last Updated: 05/03/2025 at 9:58 PM ET

Minnesota Twins at Boston Red Sox 05/04/25 - MLB Picks & Predictions
Game Start: 5/4/2025, 5:35 PM UTC
Latest Odds: BOS -225 ; O/U 8

Twins vs Red Sox Prediction

Historic Fenway Park will play host to a Sunday afternoon MLB clash between the Minnesota Twins and the Boston Red Sox. Be ready for the baseball season with all of our MLB predictions. The Twins (14-20) have dropped 14 of their first 19 road games and are 7.5 games back in the AL Central Division standings. Last night, SP Bailey Ober (4-1) allowed one run in six innings to lead Minnesota to a 4-3 road victory against Boston.  

Twenty-nine year old righty Chris Paddack (0-3 5.60 ERA) has pitched better than his record would indicate. The Twins are winless in Paddack’s previous four starts, but he has given up just five runs over his last 20 innings. 

The Boston Red Sox are two games above .500 at home and trail AL East Division leading New York by two games. During Saturday’s home loss, Boston batters went 2-for-8 with runners in scoring position and left ten men on base. SP Hunter Dobbins (2-1) gave up four runs in five plus innings and took the loss for the Red Sox, who fell to 18-17 overall.

Boston manager Alex Cora will turn to talented left-hander Garrett Grochet (3-2 2.05 ERA) in the series finale. Through 44 innings of work, Crochet has allowed two long balls and fanned 50 batters while posting a sparkling 1.05 WHIP.

Twins vs Red Sox Pick Analysis

Boston 1B Triston Casas suffered a ruptured left patellar tendon on Friday and is expected to miss the remainder of the season. Through 34 games, Minnesota ranks 22nd in OPS and 19th in runs scored. For the season, Boston ranks 6th in OPS and 3rd in runs scored. Take the under. Final Score Prediction, Boston Red Sox win 5-1.

Our Free MLB Pick for Boston Red Sox vs Minnesota Twins

UNDER 8