Twins vs Orioles Picks and Prediction – 5/15/2025

By: Eddie Kline |

Last Updated: 05/14/2025 at 10:20 PM ET

Minnesota Twins at Baltimore Orioles 05/15/25 - MLB Picks & Predictions
Game Start: 5/15/2025, 4:35 PM UTC
Latest Odds: BAL -135 ; O/U 9

Twins vs Orioles Prediction

Beautiful Camden Yards will play host to a Thursday afternoon MLB clash between the Minnesota Twins and the Baltimore Orioles. Be ready for the baseball season with all of our MLB predictions. The Twins (23-20) have reeled off ten straight victories and remain five games out of first place in the AL Central Division. In the first game of yesterday’s doubleheader, C Christian Vasquez hit a go ahead three-run blast to propel Minnesota to a 6-3 road victory against Baltimore. 

Twenty-nine year old righty Chris Paddack (1-3 4.76 ERA) will take the mound for the Twins in this matchup. Last time out, Paddack (7.1 IP) allowed three hits and one run during a 3-1 home victory versus San Francisco. 

The Baltimore Orioles have dropped eight of their last ten games and are trapped in the AL East Division basement. In the second game of Wednesday’s doubleheader, Baltimore OF Cedric Mullins’ grand slam was not enough during an 8-6 home loss. RP Yennier Cano surrendered three runs in the eighth inning and took the loss for the Orioles (15-26), who fell to 8-11 at home. 

Thirty-five year old righty Tomoyuki Sugano (4-2 2.72 ERA) has been one of the few bright spots on a dismal Baltimore pitching staff. In his last start, Sugano lasted seven plus innings and allowed one run during a 4-1 road victory against Los Angeles. 

Twins vs Orioles Pick Analysis

Baltimore 2B Jordan Westburg (hamstring) suffered a setback and has paused his running progression. Through 43 games, Minnesota ranks 22nd in OPS and 22nd in runs scored. For the season, Baltimore ranks 21st in OPS and 26th in runs scored. Take the under. Final Score Prediction, Baltimore Orioles win 4-3.

Our Free MLB Pick for Baltimore Orioles vs Minnesota Twins

UNDER 9