Brewers vs Cardinals Picks and Prediction – 4/26/2025

NL Central Division rivals will square off on Saturday afternoon, when the Milwaukee Brewers take on the St. Louis Cardinals from Busch Stadium. Be ready for the baseball season with all of our MLB predictions. The Brewers (13-14) have dropped ten of their first 14 road games and trail Chicago by four games for first place. Last night, Milwaukee OF Jackson Chourio went 2-for-4 and scored a run during a 3-2 road loss against St. Louis. 

Twenty-four year old righty Quinn Priester (1-0 1.93 ERA) will take the mound for the Twins in this matchup. Last time out, Priester (4 IP) walked four batters and gave up two runs during a 5-2 road loss against San Francisco. 

The St. Louis Cardinals have won nine of their first 13 home games and are 5.5 games off the pace in the division race. During Friday’s home victory, OF Lars Nootbaar singled and scored a run in the fifth inning to stake St. Louis to a 3-0 advantage. SP Matthew Liberatore (2-2) allowed two runs (1 ER) in six innings to earn the win for the Cardinals, who improved to 11-15 overall. 

The Cardinals will counter with thirty-five year old righty Sonny Gray (3-0 3.41 ERA) on Saturday. Through 29 innings of work, Gray has allowed five long balls and fanned 29 batters while posting a minuscule 0.86 WHIP.

Milwaukee OF Blake Perkins (shin) has resumed baseball activities and hopes to return to the lineup by the middle of May. Through 27 games, Milwaukee ranks 18th in OPS and 4th in runs scored. For the regular season, St. Louis ranks 5th in OPS and 8th in runs scored. Take the Brewers to win on the road. Final Score Prediction, Milwaukee Brewers win 4-3.