Brewers vs Pirates Picks and Prediction – 5/23/2025

NL Central Division foes will square off on Friday night, when the Milwaukee Brewers face the Pittsburgh Pirates from PNC Park. Be ready for the baseball season with all of our MLB predictions. The Brewers (25-26) are six games below .500 on the road and are 5.5 games out of first place. Last night, DH Christian Yelich homered twice and drove in four runs to power Milwaukee to an 8-5 road victory against Pittsburgh.  

Twenty-eight year old righty Freddy Peralta (5-3 2.59 ERA) will take the mound for the Brewers in this matchup. In his last start, Peralta (5 IP) allowed one run and retired five batters by strikes during a 5-2 home victory versus Minnesota. 

The Pittsburgh Pirates have dropped seven of their previous ten games and own the second worst record in the National League. During Thursday’s home loss, Pittsburgh leadoff hitter Oneil Cruz reached base three times and scored twice. SP Mike Burrows (0-1) gave up four runs in five innings and took the loss for the Pirates (17-34), who fell to 11-15 at home. 

The Pirates will counter with NL Rookie of the Year Paul Skenes (3-5 2.44 ERA) on Friday. Through 62 plus innings, Skenes has surrendered just four long balls and struck out 62 batters while posting a sparkling 0.94 WHIP. 

Pittsburgh SP Jared Jones underwent Tommy John surgery on Wednesday and will be sidelined until next season. Through 51 games, Milwaukee ranks 27th in OPS and 13th in runs scored. For the season, Pittsburgh ranks 30th in OPS and 30th in runs scored. Take the under. Final Score Prediction, Pittsburgh Pirates win 3-1.