Brewers vs Pirates Picks and Prediction – 5/22/2025

By: Cameron Ross |

Last Updated: 05/21/2025 at 9:56 PM ET

Milwaukee Brewers at Pittsburgh Pirates 05/22/25 - MLB Picks & Predictions
Game Start: 5/22/2025, 10:40 PM UTC
Latest Odds: MIL -124 ; O/U 9

Brewers vs Pirates Prediction

The Milwaukee Brewers will be back on the road Thursday night with game one of four in Pittsburgh against the Pittsburgh Pirates. Milwaukee has 24 wins on the year coming into this matchup following a successful series in Baltimore. Offensively Milwaukee has been mediocre this season with a .230 team batting average having scored 208 runs on 370 hits. The Milwaukee pitching has been shaky all season with the 4.09 team ERA. Stay in the action with our MLB Picks.

Rhys Hoskins leads the Milwaukee offense this season with a .297 batting average. Bryce Turang has a .297 batting average as well to go along with the team leading 51 hits. Christian Yelich is one of two players on the roster with seven home runs and leads Milwaukee with 26 RBI's. Jackson Chourio is the other player on the team with seven home runs to go along with 25 RBI's in 48 games played.

The Pittsburgh Pirates stay at home Thursday with17 wins and 33 losses on the year riding a 2 game-winning streak following a 2 run victory against Cincinnati on Wednesday. Offensively, Pittsburgh has been terrible this season with a .216 batting average. The Pirates have scored just 140 three-run innings on 348 hits. The Pittsburgh pitching has fared well enough however with a 4.03 ERA and the Pirates have allowed just one run during their two game-winning streak.

Joey Bart is the offensive leader this season for Pittsburgh with a .262 batting average and a .373 OBP. O'Neil Cruz leads the team with eight home runs and carries a .221 batting average. Bryan Reynolds has a .203 batting average but leads Pittsburgh this season with 24 RBIs on the year. Ke’Bryan Hayes has a .247 batting average and leads Pittsburgh with 43 hits in 47 games.

Brewers vs Pirates Pick Analysis

The. Brewers are having the better year coming into this game and will continue that trend. Pittsburgh sends a terrible pitcher to the mound that will spark the Milwaukee bats. Take the Brewers Thursday on the road to get the win in Pittsburgh. Final Score Prediction, Milwaukee Brewers win 6-2.

Our Free MLB Pick for Pittsburgh Pirates vs Milwaukee Brewers

Milwaukee Brewers -124