Brewers vs Twins Picks and Prediction – 6/21/2025

The Milwaukee Brewers open a three-game series on the road Friday versus the Minnesota Twins. Milwaukee is 39-35 following Tuesday’s 5-3 loss to the Chicago Cubs. Milwaukee’s game scheduled for Wednesday was postponed due to rain. The Brewers have lost two of the last three and trail the first-place Chicago Cubs by 6 ½ games in the National League Central. Keep up to date with all the MLB action with our expert MLB picks.

Sal Frelick is batting .289 to lead Milwaukee, while Christian Yelich is the leader in home runs with 14 and RBI with 43. Jackson Chourio is the leader in hits with 81, and Brice Turang leads in on-base percentage at .354. Milwaukee is batting .237 with a .366 slugging percentage. On Friday, Milwaukee will send Freddy Peralta to the mound. The right-hander is 6-4 with a 2.60 ERA, 84 Ks, and 32 BBs.

The Minnesota Twins dropped to 36-37 following Wednesday’s 4-2 loss to the Cincinnati Reds. Minnesota has lost each of the last six games and seven of the last eight. The Twins conclude a three-game series with Cincinnati on Thursday. Minnesota is third in the American League Central, 10 ½ games behind the first-place Detroit Tigers. 

Byron Buxton is batting .274 with 13 home runs and 43 RBI to lead Minnesota in the three categories. Ty France is the leader in hits with 68, and Ryan Jeffers is the leader in on-base percentage at .348. Minnesota is batting .241 with a .388 slugging percentage. On Friday, Minnesota will send Joe Ryan to the mound. The right-hander is 7-2 with a 2.93 ERA, 89 Ks, and 17 BBs.

Milwaukee will win on the road Friday when visiting Minnesota, but the play here is UNDER. The UNDER has cashed in four of Milwaukee's last five and four of Minnesota's last five versus an opponent from the National League. Milwaukee starter Freddy Peralta has had two consecutive strong outings, allowing one run on five hits across 12 innings. Minnesota starter Joe Ryan has had two consecutive solid outings, allowing four runs on six hits across 12 innings. Final Score Prediction: Milwaukee Brewers win by our best play is UNDER 4-2.