Brewers vs Guardians Picks and Prediction – 5/13/2025

By: Eddie Kline |

Last Updated: 05/12/2025 at 11:32 PM ET

Milwaukee Brewers at Cleveland Guardians 05/13/25 - MLB Picks & Predictions
Game Start: 5/13/2025, 10:10 PM UTC
Latest Odds: CLE -125 ; O/U 9

Brewers vs Guardians Prediction

The Tuesday MLB schedule will get underway with an interleague matchup between the Milwaukee Brewers and the Cleveland Guardians from Progressive Field. Be ready for the baseball season with all of our MLB predictions. The Brewers (20-22) are seven games below .500 on the road and are four games out of first place in the NL Central Division. Last night, Milwaukee batters left 11 men on base during a 5-0 road loss against Cleveland.

Twenty-four year old righty Quinn Priester (1-1 5.08 ERA) will make his sixth start of the year for the Brewers. Control has been a major issue for Priester, who has walked 19 batters in just 28 plus innings. 

The Cleveland Guardians have won 13 of their first 20 home games and trail AL Central Division leading Detroit by 2.5 games. During Monday’s home victory, SS Gabriel Arias went 2-for-4 and drove in three runs to lead the Cleveland offense. Kolby Allard tossed three scoreless innings of relief for the Guardians, who improved to 24-17 overall.

Cleveland manager Stephen Vogt will give the nod to right-hander Logan Allen (1-2 4.33 ERA) on Tuesday. In his last start, Allen (4 IP) was knocked around for seven hits and three runs during an 8-6 road victory against Washington.

Brewers vs Guardians Pick Analysis

Cleveland OF Lane Thomas (wrist) will begin a rehab assignment this week and hopes to return to the lineup later this month. Through 42 games, Milwaukee ranks 24th in OPS and 13th in runs scored. For the season, Cleveland ranks 18th in OPS and 17th in runs scored. Take the over. Final Score Prediction, Cleveland Guardians win 6-5.

Our Free MLB Pick for Cleveland Guardians vs Milwaukee Brewers

OVER 9