Brewers vs White Sox Picks and Prediction – 4/30/2025

By: Garrett Beaverson |

Last Updated: 04/29/2025 at 9:44 PM ET

Milwaukee Brewers at Chicago White Sox 04/30/25 - MLB Picks & Predictions
Game Start: 4/30/2025, 11:40 PM UTC
Latest Odds: MIL -160 ; O/U 7.5

Brewers vs White Sox Prediction

The Milwaukee Brewers (14–15) continue their road trip with a matchup against the Chicago White Sox (7–21) on Wednesday night at Guaranteed Rate Field. First pitch is scheduled for 7:40 PM ET, with coverage on CHSN and FanDuel Sports Network Wisconsin+. The Brewers aim to climb back to .500, while the White Sox look to snap a four-game home losing streak.​ Get in on the action with our free MLB picks.

The Brewers enter the game with a 14–15 record, having won 10 of the 14 games in which they were listed as the moneyline favorite this season . Right-hander Tobias Myers (0–0, 4.50 ERA) is expected to make his second start of the season after recovering from an oblique injury. Offensively, rookie outfielder Jackson Chourio has been a bright spot, posting a .737 slugging percentage and 1.158 OPS over the past week .​

The White Sox, struggling with a 7–21 record, will send rookie right-hander Shane Smith (1–1, 2.30 ERA) to the mound. Smith has been impressive, with opponents hitting just .177 against him and only one home run allowed. Offensively, Lenyn Sosa leads the team with a .271 batting average and 26 hits, while Andrew Benintendi has contributed four home runs . Despite recent improvements, the White Sox bullpen has been a concern, with the team recording only one save this season.

Brewers vs White Sox Pick Analysis

The Brewers are quickly becoming a team we want to fade this season, with their inconsistent offense and inability to close out games. However, the White Sox are among the worst teams in the league. We will jump on the Brewer wagon again, for now. We will back the Brewers to win this one 4-2.

Our Free MLB Pick for Chicago White Sox vs Milwaukee Brewers

Milwaukee Brewers -160