Brewers vs Cubs Picks and Prediction – 6/19/2025

On Wednesday, the Milwaukee Brewers (39-34) face off against the Chicago Cubs (44-28) at Wrigley Field in Chicago, Illinois. Keep up to date with all the MLB action, with our expert MLB picks.

Chicago comes into this matchup on a two-game winning streak and has won three of their last five games prior to their series opener against Milwaukee. In a dramatic extra-innings showdown against the Pirates, the Chicago Cubs pulled off a 3-2 walk-off victory in ten innings. Ian Happ played a key role, recording one hit in four at-bats, scoring a run, and ultimately driving in the game-winning run for his team. Looking at the Cubs' offensive leaders this season, Pete Crow-Armstrong currently sits at the top of the team’s home run leaderboard with eighteen homers. Close behind is Seiya Suzuki, who has launched seventeen long balls and stands as Chicago’s second-leading home run hitter. Suzuki has also been a major run producer for the Cubs, tallying a team-best 58 RBIs so far. Meanwhile, Nico Hoerner has been the Cubs’ most consistent hitter at the plate, leading the club with a .288 batting average this season. Despite these individual achievements, the Cubs’ offense has struggled lately, scoring just 2.2 runs per game over their last five contests. Even so, the team maintains a 5.5-game advantage over the Brewers in the NL Central standings. As Chicago looks to widen their lead atop the division, improving their recent offensive performance will be crucial. Overall, the Cubs are averaging a solid 5.3 runs per game, but they’ll need to regain that form to keep their division rivals at bay.

Milwaukee enters this game on a one-game winning streak and has won three of their last five games prior to their series opener against Chicago. In Milwaukee’s narrow 3-2 victory over St. Louis, Christian Yelich delivered an impressive performance at the plate, going 3-for-4, including a home run. He also contributed by scoring a run and driving in another with an RBI. So far this season, Yelich has been Milwaukee’s top power hitter, leading the team with 14 home runs. Jackson Chourio is not far behind, ranking second on the club with 12 homers. Yelich also leads the Brewers in RBIs, having tallied 43 runs batted in this year. When it comes to batting average, Sal Frelick stands out as the team leader, posting a .294 mark so far this season. Over their last five games, the Brewers have averaged 3.8 runs per contest as they try to close the gap with the Cubs in the divisional race during this series against them. On the season as a whole, Milwaukee averages 4.3 runs scored per game.

The Brewers are riding a wave of momentum, particularly impressive when playing away from home, where they've consistently managed to put runs on the board. They'll travel to Wrigley to take on the Cubs, who have been equally formidable, especially when playing in front of their own fans. On the mound for Milwaukee will be Jacob Misiorowski, a promising young pitcher who has made a strong impression so far. In his limited action—just five innings pitched—Misiorowski has yet to allow an earned run and holds a spotless 1-0 record. Opposing him will be Jameson Taillon, a reliable arm for the Cubs this season. Taillon has put together a solid campaign, boasting a 7-3 record with a 3.48 ERA over the course of the season. Final Score Prediction, Chicago Cubs win 3-2.