Marlins vs Mariners Picks and Prediction – 4/27/2025

By: Thomas Pemberton |

Last Updated: 04/25/2025 at 10:57 PM ET

Miami Marlins at Seattle Mariners 04/26/25 - MLB Picks & Predictions
Game Start: 4/27/2025, 1:40 AM UTC
Latest Odds: SEA -220; O/U 7.5

Marlins vs Mariners Prediction

The Seattle Mariners remain at home for their weekend series against the Miami Marlins. Seattle leads the AL West with a 14-11 record. The Mariners have won seven of their last ten games. Seattle entered this series riding a two game win streak and they carry a 8-5 home field record. Stay up to date with our expert's MLB Picks. 

Luis Castillo will make his 6th start on the mound for the Seattle Mariners. Castillo is 2-2 on the season with 26.1 innings pitched. Castillo has 23 strikeouts and carries a 4.44 ERA. Castillo pitched 5 innings in his last outing allowing 10 hits. The Seattle Mariners carry a 3.92 team ERA. 

The Miami Marlins entered this series with a 11-13 record. Miami has won four of their last ten games. The Marlins carry a 3-5 road record. Miami is averaging 4.4 runs scored per game with 9 hits. 

Connor Gillispie will make his 6th start on the hill for the Miami Marlins. Gillispie is 0-2 on the season with 24 innings pitched. Gillispie has 21 strikeouts and carries a 6.75 ERA. Gillispie pitched 5 innings in each of his last two starts. The Miami Marlins carry a 4.89 team ERA. 

Marlins vs Mariners Pick Analysis

Both starting pitchers are hoping for quality outings. Connor Gillispie hasn't earned a win yet and carries an ERA over 6. Both the Seattle Mariners and Miami Marlins are averaging over 4 runs per game. The value is in the total. Final Score Prediction, Seattle Mariners win, but the play is on the over 6-5.

Our Free MLB Pick for Seattle Mariners vs Miami Marlins

OVER 7.5