Marlins vs White Sox Picks and Prediction – 5/10/2025

By: David Anicetti |

Last Updated: 05/09/2025 at 9:26 PM ET

Miami Marlins at Chicago White Sox 05/10/25 - MLB Picks & Predictions
Game Start: 5/10/2025, 11:10 PM UTC
Latest Odds: CWS -110 ; O/U 8

Marlins vs White Sox Prediction

The Miami Marlins play the second game of a three-game series on the road Friday versus the Chicago White Sox. Miami is 14-22 following its 10-1 loss to the Los Angeles Dodgers on Wednesday. Miami is last in team ERA in baseball at 5.86. The Marlins have lost nine of the last 11 and are last in the National League East, nine games behind the first-place New York Mets. Keep up to date with all the MLB action with our MLB previews.

Kyle Stowers is batting .303 with 25 RBI and an on-base percentage of .375 to lead Miami in the three categories. Matt Mervis is the leader in home runs with seven, and Xavier Edwards is the leader in hits with 37. Miami is batting .249 with a .380 slugging percentage. On Saturday, Miami will send Edward Cabrera to the mound. The right-hander is 0-1 with a 6.29 ERA, 24 Ks, and 12 BBs.

The Chicago White Sox dropped to 10-28 following Thursday’s 10-0 loss to the Kansas City Royals. Chicago was swept in its four-game series versus Kansas City, and the White Sox have lost five of the last six. Chicago is 27th in runs scored. Chicago is last in the American League Central, 15 games behind the first-place Detroit Tigers.

Lenya Sosa is batting .248 to lead Chicago and has a team-best 32 hits. Andrew Benintendi is the leader in home runs with five, and Luis Robert Jr is the leader in RBI with 16. Miguel Vargas is the leader in on-base percentage at .313. On Saturday, the Chicago White Sox will send Shane Smith to the mound. The right-hander is 1-2 with a 2.41 ERA, 31 Ks, and 15 BBs.

Marlins vs White Sox Pick Analysis

The Chicago White Sox and Miami Marlins are struggling at this point in the season. The advantage here goes to Chicago playing at home and with a starting pitcher who has performed well of late. Miami starter Edward Cabrera has struggled in each of the last four outings, allowing 15 runs on 25 hits across 18.2 innings. Chicago starter Shane Smith has had three straight solid outings, allowing three runs on five hits across 15 innings. Final Score Prediction: Chicago White Sox win 7-2.

Our Free MLB Pick for Chicago White Sox vs Miami Marlins

Chicago White Sox -110