Dodgers vs Cubs Picks and Prediction – 4/23/2025

The Los Angeles Dodgers conclude a short two-game series on the road Wednesday versus the Chicago Cubs. Los Angeles is 16-7 following its 1-0 victory over the Texas Rangers on Sunday. Freddie Freeman had a sacrifice fly to drive in the only run, and six relievers held the Rangers scoreless. Los Angeles is tied for first in the National League West with San Diego. Keep up to date with all the MLB action with our expert MLB picks.

Shohei Ohtani is batting .277 with 23 hits and an on-base percentage of .375 to lead the Dodgers in the three categories. Tommy Edman leads Los Angeles with seven home runs, and Teoscar Hernandez is the leader in RBI with 17. LA is batting .227 with a .415 slugging percentage. Los Angeles has not announced its starting pitcher for Wednesday’s game with Chicago.

The Chicago Cubs dropped to 14-10 following Sunday’s 3-2 loss to the Arizona Diamondbacks. Chicago was off on Monday. Despite Sunday's loss, Chicago won two out of three versus Arizona. Chicago has won five of the last eight. The Cubs hold a 1 ½-game lead over second-place Milwaukee at the top of the National League Central.

Michael Busch is batting .316 to lead Chicago. Kyle Tucker leads Chicago in home runs with six, RBI with 23, hits with 29, and on-base percentage with .404. Chicago is batting .258 with a .447 slugging percentage. On Wednesday, the Chicago Cubs will send Matthew Boyd to the mound. The left-hander is 1-2 with a 2.01 ERA, 20 Ks, and 9 BBs.

Los Angeles has won five of its last six overall, four of the last six versus Chicago, and nine of the last 12 playing on the road versus the Cubs. Chicago starter Matthew Boyd gave up three runs on four hits across six innings in a 3-0 loss to the Dodgers on April 11. Boyd has allowed five runs over the last 11.1 innings. Chicago has struggled a bit of late, at 3-3 over the last six. Final Score Prediction: Los Angeles Dodgers win 8-2.