Angels vs Astros Picks and Prediction – 4/12/2025

By: Cameron Ross |

Last Updated: 04/11/2025 at 9:01 PM ET

Los Angeles Angels at Houston Astros 04/12/25 - MLB Picks & Predictions
Game Start: 4/12/2025, 11:10 PM UTC
Latest Odds: HOU -148 ; O/U 9

Angels vs Astros Prediction

The Los Angeles Angels will be on the road again Saturday with the game in Houston for game two of three against the Houston Astros. Los Angeles has eight wins and four losses on the year coming into this matchup having won for the last five following a 10 run road victory against Tampa Bay last time out. Offensively Los Angeles has done the job this season with a .2318 batting average as the Angels have scored 65 runs on 98 hits here the angel's power has been phenomenal as well with 24 home runs and a .457 team slugging percentage. Stay in the action with our MLB Picks.

Logan O’Hoppe leads the Los Angeles offense this season with a .359 batting average. Nolan Schauel has been vital for Los Angeles as well this season with a .289 batting average through 12 games played. Mike Trout supplies the power for the Los Angeles offense with five home runs and eleven RBI's this season.

The Houston Astros will be at home Saturday two games below .500 on the year having lost three of the last five following a one run road loss to Seattle. Offensively Houston has struggled all season with a .208 batting average. The Astros scored just 38 runs on three hits this season. The Houston pitching has fared well however with a 3.78 team ERA.

Jose Altuve leads the Houston offense this season with a .346 batting average and three home runs on the year. Isaac Paredes has been solid for the Astros with a .234 batting average, and Brendan Rodgers has chipped in with a .250 batting average. Big man Yordan Alvarez leads Houston this season with eight RBIs in 12 games playing.

Angels vs Astros Pick Analysis

The Angels have been the better team this season but Houston will be at home with the better arm. Look for Houston to continue to play well in this game leading to the win. Take the Astros Saturday to get it done leading to the win at home. Final Score Prediction, Houston Astros win 6-2.

Our Free MLB Pick for Houston Astros vs Los Angeles Angels

Houston Astros -148