Angels vs Astros Picks and Prediction – 4/12/2025

By: Dylan Hellebrand |

Last Updated: 04/10/2025 at 9:31 PM ET

Los Angeles Angels at Houston Astros 04/11/25 - MLB Picks & Predictions
Game Start: 4/12/2025, 12:10 AM UTC
Latest Odds: HOU -152 ; O/U 9

Angels vs Astros Prediction

On Friday, the Los Angeles Angels (7-3) face off against the Houston Astros (5-6) at Daikin Park in Houston, Texas. Keep up to date with all the MLB action, with our expert MLB picks.

Houston comes into this matchup on a one-game winning streak and has won three of their last five games prior to their series finale against Seattle. In a thrilling 2-1 victory over Seattle that stretched into twelve innings, Framber Valdez showcased impressive control on the mound for the Astros. He pitched six strong innings, giving up just two hits, a single walk, and no runs. This season, Jose Altuve has been a powerhouse for Houston, leading the team with three home runs. Jeremy Pena follows closely, contributing two home runs thus far. Yordan Alvarez stands out as the top RBI contributor for the Astros, racking up seven RBIs this season. Altuve also excels with the highest batting average on the team at .340. Over their past five games, Houston has averaged four runs per game and aims to secure a win against the Angels, who have started the season surprisingly well. Overall, the Astros are currently averaging 2.9 runs per game.

Los Angeles enters this game on a three-game winning streak and has won three of their last five games prior to their last two games of their series against Tampa Bay. In their 4-3 victory over Tampa Bay, Kyren Paris made a significant contribution for the Angels by going 1-for-3, including a home run that brought in two RBIs and scored a run. This season, Logan O’Hoppe has emerged as the home run leader for Los Angeles, hitting a total of five so far. Meanwhile, Kyren Paris and Mike Trout are tied as the second-highest home run hitters on the team with three each. O’Hoppe is also at the top of the leaderboard for RBIs, amassing nine. He holds the highest batting average on the team, standing at .367. In their last five games, the Angels have consistently put up an average of 6.2 runs, building momentum as they prepare to take on the Astros in Houston. Overall, they maintain an average of 5 runs per game for the season.

Angels vs Astros Pick Analysis

The Astros are aiming to elevate their offensive performance as they host the Angels in Houston. Meanwhile, the Los Angeles lineup has been performing exceptionally well and is eager to maintain their impressive run by putting pressure on Houston’s pitchers. Jack Kochanowicz, the Angels' starting pitcher, enters the game with a solid 1-0 record and a 3.27 ERA for the season. Final Score Prediction, Houston Astros win 4-3.

Our Free MLB Pick for Houston Astros vs Los Angeles Angels

Houston Astros -152