Angels vs White Sox Picks and Prediction – 3/29/2025

The Los Angeles Angels play the second game of a three-game series on the road Saturday versus the Chicago White Sox. Los Angeles is 0-1 after opening the regular season on Thursday with an 8-1 loss to the White Sox. Yusei Kikuchi’s debut for the Angels was below average, allowing three runs on five hits across six innings. The Angels' only run came in the top of the 9th inning on a home run by Logan O’Hoppe. Keep up to date with all the MLB action with our MLB picks.

After one game of the regular season, Logan O’Hoppe leads Los Angeles with a .500 batting average, one home run, one RBI, and two hits. Mike Trout is the leader in on-base percentage with .500. Los Angeles had only five hits on opening day. On Saturday, the Angels will send Jose Soriano to the mound. Last season, the right-hander was 6-7 with a 3.42 ERA, 97 Ks, and 45 BBs.

The Chicago White Sox have started the season strong with their 7-run victory over the Los Angeles Angels on Thursday. Starting pitcher Sean Burke picked up the victory with six strong innings, allowing just three hits and no runs. Chicago hit three home runs on opening day. Andrew Benintendi, Austin Slater, and Lenyn Sosa each hit one home run for the White Sox.

After one game of the regular season, Miguel Vargas is batting .500, with two hits and an on-base percentage of .500 to lead Chicago in each category. Andrew Benintendi is one of three players with one home run and the leader in RBI with three. On Saturday, the Chicago White Sox will send Jonathan Cannon to the mound. Last season, the right-hander was 5-10 with a 4.49 ERa, 91 Ks, and 40 BBs.

Los Angeles is coming off a poor start to its 2025 MLB regular season, as the Angels had just five hits and lost to Chicago 8-1 on Thursday. The White Sox displayed power on opening day with three home runs and will once again hit Los Angeles’ pitching well on Saturday. The White Sox scored eight runs and had a .606 slugging percentage on Opening Day. Final Score Prediction, Chicago White Sox win 6-3.