Angels vs Red Sox Picks and Prediction – 6/4/2025

Historic Fenway Park will play host to a Wednesday afternoon MLB clash between the Los Angeles Angels and the Boston Red Sox. Be ready for the baseball season with all of our MLB predictions. The Angels (28-32) are a game above .500 on the road and are five games off the pace in the AL West Division race. Last night, leadoff hitter Zach Neto went 2-for-4 with a pair of runs scored to spark Los Angeles to a 4-3 road victory in ten innings. 

Twenty-six year old righty Jose Soriano (4-5 3.41 ERA) will head to the hill for the Angels in this contest. Last time out, Soriano fired six shutout frames and allowed just four hits during a 4-1 road victory against Cleveland. 

The Boston Red Sox have dropped the first two games of this series and are suddenly ten games out of first place in the AL East Division. During Tuesday’s home loss, Boston batters went 1-for-13 with runners in scoring position and left 11 men on base. OF Ceddane Rafaela fell a triple short of the cycle and plated two runs for the Red Sox (29-34), who fell to 16-16 at home. 

Thirty year old right-hander Lucas Giolito (1-1 4.78 ERA) will make his seventh start of the year for the Red Sox. Through 32 innings of work, Giolito has struck out 26 batters and owns a subpar 1.44 WHIP. 

Boston SP Kutter Crawford (knee) is expected to begin a rehab assignment this week. Through 60 games, Los Angeles ranks 20th in OPS and 20th in runs scored. For the season, Boston ranks 9th in OPS and 6th in runs scored. Take the over. Final Score Prediction, Boston Red Sox win 7-6.