Royals vs Guardians Picks and Prediction – 4/11/2025

By: David Anicetti |

Last Updated: 04/10/2025 at 2:09 PM ET

Kansas City Royals at Cleveland Guardians 04/11/25 - MLB Picks & Predictions
Game Start: 4/11/2025, 10:10 PM UTC
Latest Odds: CLE -134 ; O/U 6.5

Royals vs Guardians Prediction

The Kansas City Royals open a three-game series on the road Friday versus the Cleveland Guardians. Kansas City is 6-6 following its 4-0 loss to the Minnesota Twins on Wednesday. The loss snapped Kansas City’s three-game winning streak. The Royals are second in the American League Central, one game behind the first-place Detroit Tigers. Keep up to date with all the MLB action with our expert MLB picks.

Maikel Garcia is batting .308 to lead Kansas City and has a team-high of two home runs. Vinnie Pasquantino is the leader in RBI with 10, and Bobby Witt Jr is the leader in hits with 13. Jonathan India is the leader in on-base percentage with .365. On Friday, the Kansas City Royals will send Kris Bubic to the mound. The left-hander is 2-0 with a 0.71 ERA, 16 Ks, and 3 BBs.

The Cleveland Guardians improved to 5-6 following a 3-2 victory over the Chicago White Sox on Wednesday and will complete a three-game series with Chicago on Thursday. Carlos Santana hit a home run for Cleveland in Wednesday’s victory. Cleveland is third in the American League Central, 1 ½ games behind the first-place Detroit Tigers and a half-game behind Kansas City.

Steven Kwan is batting .300 to lead Cleveland. Jose Ramirez is the leader in home runs with four and on-base percentage with .400. Kyle Manzardo is the leader in RBI with nine, and Carlos Santana is the leader in hits with 12. Cleveland is batting .204 with a .364 slugging percentage. On Friday, Cleveland will send Tanner Bibee to the mound. The right-hander is 1-1 with a 6.52 ERA, 6 Ks, and 3 BBs.

Royals vs Guardians Pick Analysis

Kansas City has won four of its last six. Kansas City starter Kris Bubic has performed well in both outings thus far, allowing just one run on seven hits across 12.2 innings. Cleveland starter Tanner Bibee struggled last time out, allowing seven runs on 8 hits across four innings. The Royals will hit Cleveland pitching hard on Friday and win behind strong pitching from Bubic and the bullpen. Final Score Prediction, Kansas City Royals win 4-2.

Our Free MLB Pick for Cleveland Guardians vs Kansas City Royals

Kansas City Royals +114