Royals vs White Sox Picks and Prediction – 6/6/2025

The Kansas City Royals open a three-game series on the road Friday versus the Chicago White Sox. Kansas City is 32-29 following its 10-7 victory over the St Louis Cardinals on Tuesday. Kansas City’s game scheduled for Wednesday versus St Louis was postponed and will be made up as part of a doubleheader on Thursday. Kansas City is 4th in the American League Central, eight games behind first place. Keep up to date with all the MLB action with our expert MLB picks.

Maikel Garcia is batting .313 with an on-base percentage of .374 to lead Kansas City in both categories. Vinnie Pasquantino is the leader in home runs with eight. Bobby Witt Jr is the leader in RBI with 35 and hits with 68. Kansas City is batting .248 with a .362 slugging percentage. On Friday, Kansas City will send Seth Lugo to the mound. The right-hander is 3-5 with a 3.45 ERA, 45 Ks, and 17 BBs.

The Chicago White Sox dropped to 19-43 following Wednesday’s 5-4 loss to the Detroit Tigers. Chicago has lost two of the first three to Detroit in its four-game series, which concludes on Thursday. The White Sox have lost five of the last six overall. Chicago is last in the American League Central, 21 ½ games behind first-place Detroit Tigers.

Lenya Sosa is .274 with 55 hits to lead Chicago in each of the two categories. Miguel Vargas has eight home runs, 26 RBI, and an on-base percentage of .316 to lead Chicago in each of the three categories. The White Sox are batting .221 with a .342 slugging percentage. On Friday, Chicago will send Davis Martin to the mound. The right-hander is 2-6 with a 3.67 ERA, 41 Ks, and 17 BBs.

Chicago will win at home on Friday, but the play here is OVER. The OVER has cashed in three of Kansas City's last five and each of Chicago's last five played at home. Kansas City starter Seth Lugo has had two consecutive below-average outings, allowing seven runs on 11 hits across 9.1 innings. Chicago starter Davis Martin was hit hard last time out, allowing four runs on five hits across six innings. Final Score Prediction, Chicago White Sox win but our best play is OVER 7-5.