Astros vs Rays Picks and Prediction – 5/20/2025

The Houston Astros play the second game of a three-game series on the road Tuesday versus the Tampa Bay Rays. Houston is 24-22 following its 4-3 victory over the Texas Rangers on Sunday. Isaac Paredes hit a three-run homer to put Houston ahead in the eighth inning. Houston has won four of the last six and trails first place in the American League West by 2 ½ games. Keep up to date with all the MLB action with our expert MLB picks.

Jeremy Pena is batting .299 with 52 hits to lead Houston in both. Isaac Paredes is leading Houston in home runs with seven, RBI with 24, and on-base percentage at .372 to lead Houston in each category. Houston is batting .245 with a .372 slugging percentage. Houston has not yet announced its starting pitcher for Tuesday’s game versus the Tampa Bay Rays.

The Tampa Bay Rays dropped to 21-25 following Sunday’s 5-1 loss to the Miami Marlins in the final game of a three-game series in which Tampa Bay lost two of the three. Tampa Bay has alternated between wins and losses and each of the last eight games. The Rays are fourth in the American League East, six games behind the first-place New York Yankees.

Jonathan Aranda is batting .312 with 43 hits and an on-base percentage of .396 to lead Tampa Bay in each of the three categories. Junior Caminero is the leader in home runs with eight, and Yandy Diaz is the leader in RBI with 24. Tampa Bay is batting .242 with a .363 slugging percentage. On Tuesday, the Rays will send Zack Littell to the mound. The right-hander is 3-5 with a 4.31 ERA, 32 Ks, and 10 BBs.

The Tampa Bay Rays will win at home on Tuesday when hosting the Houston Astros, but the play here is UNDER. The UNDER has cashed in five of Houston's last six, six of Tampa Bay's last nine, and each of the last six that Houston has played head-to-head versus Tampa Bay. Tampa Bay starter Zack Littell has allowed five runs on 14 hits across 13.1 innings in his most recent two outings. Final Score Prediction: Tampa Bay Rays win but our best play is UNDER 4-2.