Astros vs Cardinals Picks and Prediction – 4/14/2025

The Houston Astros open a three-game series on the road Monday versus the St. Louis Cardinals. Houston dropped to 6-8 following its 4-1 loss on Saturday to the Los Angeles Angels. Houston is 4th in the American League West at 6-8, three games behind the first-place Los Angeles Angels. Houston has alternated between wins and losses in each of its last nine games. Keep up to date with all the MLB action with our MLB previews.

Jose Altuve is batting .317 with three home runs and 19 hits to lead Houston in each of the three categories. Yordan Alvarez is the leader in RBI with nine, and Isaac Paredes is the leader in on-base percentage at .391. On Monday, the Houston Astros will send Framber Valdez to the mound. The left-hander is 1-1 with a 2.50 ERA, 21 Ks, and 7 BBs.

The St Louis Cardinals dropped to 6-8 following Saturday’s 4-1 loss to the Philadelphia Phillies. St Louis opened its series versus Philadelphia with a 2-0 victory on Friday and concludes the three-game set on Sunday. The Cardinals are fourth in the National League Central, 2 ½ games behind the first-place Chicago Cubs. The Cardinals have lost five of the last seven.

Brendan Donovan is batting .357 with 20 hits to lead St. Louis in both categories. Ivan Herrera leads in home runs with four and RBI with 11 but is currently on the injury list. Lars Nootbaar is the leader in on-base percentage at .409. On Monday, the St. Louis Cardinals will send Sonny Gray to the mound. The right-hander is 2-0 with a 4.50 ERA, 19 Ks, and 2 BBs.

Houston will win on Monday when visiting St Louis, but the play here is UNDER. The UNDER has cashed in the four of Houston's last seven each of St. Louis’ last three. Houston starting pitcher Framber Valdez is coming off his best start of the season, allowing no runs on two hits across six innings last Tuesday. St Louis starter Sonny Gray is coming off a strong outing in which the right-hander allowed one run on three hits across five innings. Final Score Prediction: Houston Astros win but our best play is UNDER 4-2.