Astros vs Mariners Picks and Prediction – 7/20/2025

As the second half begins, the Houston Astros (56–41) roll into Seattle to face the Mariners (52–45) in a pivotal AL West showdown. Seattle holds a slim 4-game lead atop the division, while Astros aim to claw back with a series win. Tonight’s matchup features Hunter Brown for Houston and Bryan Woo for Seattle—both fiery young arms aiming to set a tone. Get in on all the baseball action with our free MLB picks.

Ace Hunter Brown (9–4, ~2.43 ERA) headlines, riding a dominant stretch across June, including a 28-inning scoreless streak—earning April’s Pitcher of the Month. Despite Houston's rotation injuries, Brown offers stability and ground-ball excellence. Offensively, the Astros have feasted on Seattle pitching—batting .335/.443 over their last five meetings. With Bryan Woo coming off a rough July 12 outing, Houston's bats have the upper hand tonight. The Mariners counter with Bryan Woo (8–4, ~2.75 ERA), Seattle’s strikeout machine. He’s allowed just two runs over 18 consecutive innings to start 2025, earning an All-Star nod.

After sweeping the Tigers and entering the break on hot form, Seattle relies on a potent home crowd and Cal Raleigh’s 38 HRs. But depth matters—the rotation is a bit thin, and Woo hasn't faced Houston in this series.

A classic showdown between two rising aces. Expect tight early innings, but high-leverage fireworks late. The powerful bats of the Seattle Mariners are what we want to back in these last few innings. With home run king Cal Raleigh in the order, we feel safe with a play on Seattle. Prediction: Mariners win 5-4.