Astros vs Athletics Picks and Prediction – 6/17/2025

On Monday, the Houston Astros open a four-game series on the road versus the Athletics. Houston improved to 40-30 following Saturday’s 3-2 victory over the Minnesota Twins. Cam Smith hit a walk-off RBI single in the bottom of the 9th inning for Houston. Houston has won four straight and seven of the last nine. The Astros lead the American League West by 4 ½ games. Keep up to date with all the MLB action with our MLB picks.

Jeremy Pena is batting .328 with 89 hits and an on-base percentage of .380 to lead Houston in the three categories. Isaac Paredes leads Houston in home runs with 15 and in RBI with 42. Houston is batting .255 with a .394 slugging percentage. On Monday, Houston will send Lance McCullers Jr. to the mound. The right-hander is 1-2 with a 4.91 ERA, 39 Ks, and 16 BBs.

The Athletics improved to 28-44 following Saturday’s 4-0 victory over the Kansas City Royals. Jacob Lopez threw six innings of three-hit shutout ball for the A’s, while Lawrence Butler and Max Muncy each hit home runs. The Athletics have won two straight since snapping a three-game losing streak but are last in the AL West, 13 games behind first-place Houston. 

Jacob Wilson is batting .369 with 97 hits and an on-base percentage of .404 to lead the Athletics in the three categories. Brent Rooker leads in home runs with 15, and Tyler Soderstrom has a team-high 45 RBI. The A’s are batting .254 with a .416 slugging percentage. On Monday, the Athletics will send Mitch Spence to the mound. The right-hander is 2-1 with a 3.67 ERA, 45 Ks, and 15 BBs. 

Houston has played better than the Athletics of late, but the A’s will have a starting pitcher on the mound who has performed well of late. Houston starter Lance McCullers Jr was hit hard last time out, allowing four runs on four hits across five innings. On May 28, McCullers Jr gave up three runs across six innings to the Athletics. A’s starter Mitch Spence gave up no runs, on three hits across five innings last Tuesday. Final Score Prediction: Athletics win 5-3.