Astros vs Pirates Picks and Prediction – 6/5/2025

The Houston Astros stay on the road Thursday for game three of three in Pittsburgh against the Pirates. Houston has 33 wins in 28 losses this season and have won three of the last five overall following a three run loss to Pittsburgh on Wednesday. Offensively Houston is hitting the ball well with a .252 batting average as the Astros have scored  243 runs on 502 hits. The Astros pitching has been solid as well this season with a 3.59 team ERA. Stated in the action with our MLB Picks.

Jeremy Pena leads the Houston offense this season with a .312 batting average and 72 hits on the year. Isaac Paredes has a .248 batting average and leads Houston with 12 home runs and 34 RBIs this season. Jose Altuve has a .264 batting average and Jake Meyers has a .292 batting average this season.

The Pittsburgh Pirates stay on their home field Thursday 16 games below .500 after losing 3 of the last five games overall. Offensively Pittsburgh is one of the worst teams in the league with the .226 batting average a the Pirates have scored 194 runs on 458 hits. The Pittsburgh pitching has been top tier this season with a 3.94 team ERA.

Andre McCutchen leads the Pittsburgh offense this season with a .254 batting average and a .354 OBP. Bryan Reynolds leads the team with 34 RBIs and 55 hits this season. Oneil Cruz has a .229 batting average but leads Pittsburgh with 12 home runs and 54 games played. Nick Gonzales has a .333 batting average for Pittsburgh this season but has played in just two games. Isiah Kiner-Falefa has a .304 batting average but he's played just 50 times this year.

Both teams send out solid pitchers but the Pirates are one of the worst offensive teams in the league. Take Houston to do the work on the offensive end to get the win. The Astros will do the work Thursday in Pittsburgh to get the road win. Final Score Prediction, Houston Astros win 5-1.