Astros vs Brewers Picks and Prediction – 5/7/2025

In Wednesday afternoon MLB action, the Houston Astros and the Milwaukee Brewers will wrap up their series from American Family Field. Be ready for the baseball season with all of our MLB predictions. The Astros (17-18) have dropped 11 of their first 17 road games and are 3.5 games back in the AL West Division standings. Last night, Houston 2B Brendan Rodgers’ three-run blast was not enough offense during a 4-3 road loss.

Thirty-one year old southpaw Framber Valdez (1-4 4.39 ERA) will take the mound for the Astros in this matchup. Houston has lost Valdez’s previous four starts and he has surrendered 15 runs over his last 23 innings. 

The Milwaukee Brewers have won three straight games and are 3.5 games behind NL Central Division leading Chicago. During Tuesday’s home victory, 1B Rhys Hoskins had a two-run double and OF Jake Bauers followed with a two-run blast as part of an explosive Milwaukee opening frame. SP Chad Patrick (2-3) allowed three runs in six plus innings to earn the win for the Brewers (19-18), who improved to 12-6 at home. 

Twenty-four year old righty Quinn Priester (1-0 5.79 ERA) will get the nod for the Brewers on Wednesday. Control has been a major issue for Priester, who has walked 16 batters and owns an alarming 1,76 WHIP across 23 plus frames. 

Houston 1B Yordan Alvarez has landed on the 10-day injured list with right hand inflammation. Through 35 games, Houston ranks 21st in OPS and 19th in runs scored. For the season, Milwaukee ranks 22nd in OPS and 10th in runs scored. Take the Astros to win on the road. Final Score Prediction, Houston Astros win 5-2.