Astros vs Brewers Picks and Prediction – 5/6/2025

The Houston Astros play the second game of a three-game series on the road Tuesday versus the Milwaukee Brewers. Houston is 17-16 following Sunday’s 5-4 loss to the Chicago White Sox. Houston has lost three of the last four. The Astros are third in the American League West and trail first-place Seattle by three games. Keep up to date with all the MLB action with our MLB picks.

Jeremy Pena is batting .282 to lead Houston. Jose Altuve is the leader in home runs with four and hits with 35. Yordan Alvarez is the leader in the RBI with 18, and Isaac Paredes is the leader in on-base percentage at .353. Houston is batting .243 with a .370 slugging percentage. On Tuesday, Houston will send Hayden Wesneski to the mound. The right-hander is 1-2 with a 3.86 ERA, 26 Ks, and 4 BBs.

The Milwaukee Brewers improved to 17-18 following Sunday’s 4-0 victory over the Chicago Cubs. Freddy Peralta threw six shutout innings for the Brewers. The victory snapped a three-game losing streak by Milwaukee. The Brewers are just 4-3 in the last seven. Milwaukee is third in the National League Central, four games behind first place. 

Brice Turang is batting .315 to lead Milwaukee and has a team-high of 41 hits. Jackson Chourio is the leader in home runs with six and in RBI with 24. Rhy Hoskins is the leader in on-base percentage at .381. Milwaukee is batting .238 with a .356 slugging percentage. On Tuesday, Milwaukee will send Chad Patrick to the mound. The right-hander is 1-3 with a 2.87 ERA, 26 Ks, and 11 BBs.

Milwaukee has won 10 of the last 15 at home, and the Brewers have won six of the last eight versus an opponent from the American League. Houston has lost six of the last 9 versus an opponent from the National League. Houston starter Hayden Wesneski has allowed 12 runs across the last 28 innings. Milwaukee starter Chad Patrick was hit hard last time out, allowing three runs on six hits across 5.2 innings, but maintains a solid 2.87 ERA. Final Score Prediction: Milwaukee Brewers win 7-3.